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B


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Baltimore, David (11/9/2006)
Working independently, David Baltimore hypothesized that the mechanism for converting RNA to DNA could be found in the RNA virus particle itself.
Bittner (1904-1961), John (11/9/2006)
John Joseph Bittner proposed that breast cancer in mice was transmitted by a factor present in mouse milk.
Bottjer, Sarah (9/8/2008)
Bottjer was the first scientist to observe that disabling a young finch's learning pathway in the brain stops the learning in midstream.
 

C


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Capecchi, Mario R. (2/13/2009)
In 2007 Mario Capecchi used a sophisticated version of gene targeting to discover the hidden origin of a rare childhood cancer, synovial sarcoma that currently has no cure or effective treatment.
Cheng, Keith (11/9/2006)
Keith Cheng envisioned the importance of the zebrafish as a vertebrate model for medical research, particularly for finding new genes related to human cancer.
 

F


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Frei III, Emil (11/9/2006)
Pediatric oncologists Emil Frei and Emil J. Freireich were part of a team invited to conduct clinical studies in the Chemotherapy Program of the National Cancer Institute.
Freireich, Emil J (11/9/2006)
Pediatric oncologists Emil Frei and Emil J. Freireich were part of a team invited to conduct clinical studies in the Chemotherapy Program of the National Cancer Institute
 

J


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Jin, Peng (2/13/2009)
While working in a laboratory focused on fragile X, Peng Jin began to think that the different mutations of this gene seen in carriers of fragile X syndrome might be responsible for the neurological problems some of these people had later in life.
 

K


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Kandel, Eric (9/8/2008)
By uncovering the basic molecular building blocks of memory, Eric Kandel opened the door to discovering how the brain makes memories, thoughts, and emotions, and triggers learning and certain behaviors.
 

L


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Law (1910-2002), Lloyd (11/9/2006)
Lloyd Law observed that treating leukemic animals with a single drug produced only temporary remission of the disease. He reasoned that administering a single agent killed the sensitive cells but resulted in the production of mutant cells. He proposed that using more than one drug, that is, combination chemotherapy, would be more effective in eradicating all the leukemic cells.
Little (1888-1971), Clarence Cook (11/9/2006)
Clarence Cook Little, known as “CC Little" promoted the idea that the best way to study cancer was through experiments on mouse genetics using cells from inbred mice.
 

M


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Mignot, Emmanuel (9/15/2008)
Intrigued by what causes us to fall asleep, psychiatrist Dr. Emmanuel Mignot spearheaded the hunt for the gene that causes narcolepsy in dogs. His research on these animals is leading to new treatments for this unusual sleep disorder in people.
 

P


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Perez, John (9/15/2008)
Intrigued by the medical potential of snake venom, Dr. John Perez founded the Natural Toxins Researcher Center, the only federally funded serpentarium. At this center, poisonous snakes are raised and milked for their venom, which is then sent to researchers.
 

R


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Rous (1879-1970), Peyton (11/9/2006)
Contrary to the thinking of the time, Rous was convinced that tumors in chickens were caused by an infectious agent or agents, giving credence to the idea that viruses can cause cancer.
 

S


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Stein, Donald (8/22/2008)
Don Stein worked with rats to understand how progesterone could protect the brain after traumatic injury. This work led to the only clinical trial in TBI to show marked improvement in patients.
Storrs, Eleanor (11/2/2006)
Leprosy research was handicapped for many years because scientists could not find an animal model to study the disease. Eleanor Storrs proposed that the nine-banded armadillo might be the sought-after model because of its low body temperature, longevity, and susceptibility to human diseases.
 

T


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Temin (1934-1994), Howard Martin (11/9/2006)
Howard Temin challenged the scientific establishment by proposing that genetic information could flow from RNA to DNA. His idea was considered scientific heresy because dogma at that time held that genetic material flowed only from DNA to RNA.
 

V


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Varmus, Harold (11/9/2006)
While conducting research on oncogenes, or cancer-causing genes, Harold Varmus hypothesized that cancerous cells arise from the alteration of a normal cellular gene.
 

W


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Warren, Stephen (2/13/2009)
While still a post-doctoral student, Stephen Warren became convinced that a single gene was necessary to cause fragile X syndrome -- the most common form of mental retardation in humans – and that this gene operated in a way unlike that of any other cause of mental retardation.
Wright, David (8/22/2008)
David Wright, in the hallway at Grady memorial Hospital’s trauma center, is a bench to bedside researcher, taking animal research studies to the next step to improve care for patients.